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Assay Detail

CHEMBL5231113

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human WM-115 cells incubated for 72 hrs by celltiter glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type WM-115
Confidence 1 — Organism
Curated By Autocuration

Target

WM-115 (CHEMBL1075611)
Type CELL-LINE
Organism Homo sapiens

Publication

Systemic review on B-Raf<sup>V600E</sup> mutation as potential therapeutic target for the treatment of cancer.
Chavda J, Bhatt H.
Eur J Med Chem (2020) 206 : 112675 -112675
PubMed 32798788 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.83 6.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5283675 1 6.83

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5283675 IC50 = 148.0 nM 6.83