Assay Detail
Functional
CHEMBL5231114
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human COLO 205 cells incubated for 72 hrs by celltiter glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | COLO 205 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Systemic review on B-Raf<sup>V600E</sup> mutation as potential therapeutic target for the treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.30 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5283675 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5283675 | — | IC50 | = | 5.0 | nM | 8.30 |