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Assay Detail

CHEMBL5231645

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytoprotective activity against KCN induced-toxicity in rat PC-12 cells assessed as reduction in cell death for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Cell Type PC-12
Confidence 1 — Organism
Curated By Autocuration

Target

PC-12 (CHEMBL612556)
Type CELL-LINE
Organism Rattus norvegicus

Publication

Natural products and other inhibitors of F<sub>1</sub>F<sub>O</sub> ATP synthase.
Patel BA, D'Amico TL, Blagg BSJ.
Eur J Med Chem (2020) 207 : 112779 -112779
PubMed 32942072 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.10 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5271072 1 8.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5271072 IC50 = 8.0 nM 8.10