Assay Detail
Binding
CHEMBL5231663
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 10 mins followed by substrate addition and measured for 20 mins by Fluorescence microplate reader assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.42 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL454320 | TRICIN | — | 1 | 6.60 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.82 |
| CHEMBL5286281 | — | — | 1 | 5.21 |
| CHEMBL5286540 | — | — | 1 | 5.02 |
| CHEMBL164 | MYRICETIN | — | 1 | 5.00 |
| CHEMBL5276356 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL454320 | TRICIN | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL50 | QUERCETIN | IC50 | = | 1520.0 | nM | 5.82 |
| CHEMBL5286281 | — | IC50 | = | 6120.0 | nM | 5.21 |
| CHEMBL5286540 | — | IC50 | = | 9520.0 | nM | 5.02 |
| CHEMBL164 | MYRICETIN | IC50 | = | 9930.0 | nM | 5.00 |
| CHEMBL5276356 | — | IC50 | = | 13060.0 | nM | 4.88 |