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Assay Detail

CHEMBL5231701

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human MAO-B using benzylamine as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review.
Manzoor S, Hoda N.
Eur J Med Chem (2020) 206 : 112787 -112787
PubMed 32942081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.60 5.61

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL105360 1 5.61
CHEMBL105350 BISDEMETHOXYCURCUMIN 1 5.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL105360 IC50 = 2450.0 nM 5.61
CHEMBL105350 BISDEMETHOXYCURCUMIN IC50 = 2590.0 nM 5.59