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Assay Detail

CHEMBL5232453

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Binding
Inhibition of BRD9 (unknown origin) by Isothermal titration calorimetry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bromodomain-containing protein 9 (CHEMBL3108640)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

From Hit Seeking to Magic Bullets: The Successful Union of Epigenetic and Fragment Based Drug Discovery (EPIDD + FBDD).
Vaidergorn MM, da Silva Emery F, Ganesan A.
J Med Chem (2021) 64 : 13980 -14010
PubMed 34591474 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 3 6.61 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3753082 1 7.00
CHEMBL5267719 1 6.21
CHEMBL216146 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3753082 Kd = 99.0 nM 7.00
CHEMBL5267719 Kd = 612.0 nM 6.21
CHEMBL216146 Kd = 5.0 nM -