Assay Detail
Functional
CHEMBL5232913
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human NCI-H2170 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H2170 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of new arjunolic acid derivatives as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.82 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287348 | — | — | 1 | 5.89 |
| CHEMBL5290913 | — | — | 1 | 5.88 |
| CHEMBL5285773 | — | — | 1 | 5.82 |
| CHEMBL5273489 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287348 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL5290913 | — | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL5285773 | — | IC50 | = | 1510.0 | nM | 5.82 |
| CHEMBL5273489 | — | IC50 | = | 2110.0 | nM | 5.68 |