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Assay Detail

CHEMBL5233335

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HSV-2 by plaque reduction neutralization test
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human alphaherpesvirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

Human alphaherpesvirus 2 (CHEMBL370)
Type ORGANISM
Organism Human alphaherpesvirus 2

Publication

Expanding the repertoire of methanocarba nucleosides from purinergic signaling to diverse targets.
Jacobson KA, Salmaso V, Suresh RR, Tosh DK.
RSC Med Chem (2021) 12 : 1808 -1825
PubMed 34825182 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL146673 (NORTH)-METHANOCARBATHYMIDINE 1.0 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL146673 (NORTH)-METHANOCARBATHYMIDINE IC50 = 250.0 nM 6.60