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Assay Detail

CHEMBL5233392

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of fluorescent labeled mannosylated BSA probe to DC-SIGN (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

C-type lectin domain family 4 member M (CHEMBL2176858)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN.
Cramer J.
RSC Med Chem (2021) 12 : 1985 -2000
PubMed 35024612 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1503347 1 5.80
CHEMBL5268319 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1503347 IC50 = 1600.0 nM 5.80
CHEMBL5268319 IC50 = 1600.0 nM 5.80