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Assay Detail

CHEMBL5233549

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Induction of apoptosis in human MDA-MB-468 cells incubated for 24 hrs by ELISA assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-468
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-468 (CHEMBL614335)
Type CELL-LINE
Organism Homo sapiens

Publication

Revisiting signal transducer and activator of transcription 3 (STAT3) as an anticancer target and its inhibitor discovery: Where are we and where should we go?
Huang Q, Zhong Y, Dong H, Zheng Q, Shi S, Zhu K, Qu X, Hu W, Zhang X, Wang Y.
Eur J Med Chem (2020) 187 : 111922 -111922
PubMed 31810784 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.14 6.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2031566 1 6.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2031566 EC50 = 730.0 nM 6.14