Assay Detail
Binding
CHEMBL5234368
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Inhibition of Staphylococcus aureus DHFR F98Y mutant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Dihydrofolate reductase inhibitors for use as antimicrobial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.33 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1235617 | — | — | 1 | 8.74 |
| CHEMBL5284400 | — | — | 1 | 6.96 |
| CHEMBL4483572 | — | — | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1235617 | — | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL5284400 | — | IC50 | = | 111.0 | nM | 6.96 |
| CHEMBL4483572 | — | IC50 | = | 510.0 | nM | 6.29 |