Assay Detail
Binding
CHEMBL5234388
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIV-1 protease
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 protease (CHEMBL243) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Design and discovery of boronic acid drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 10.85 | 10.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5274743 | — | — | 1 | 10.89 |
| CHEMBL5288702 | — | — | 1 | 10.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5274743 | — | Ki | = | 0.0129 | nM | 10.89 |
| CHEMBL5288702 | — | Ki | = | 0.0155 | nM | 10.81 |