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Assay Detail

CHEMBL5234422

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to MCT1 in rat Erythrocyte assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Cell Type Erythrocyte
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Monocarboxylate transporter 1 (CHEMBL2073709)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Monocarboxylate transporter 1 and 4 inhibitors as potential therapeutics for treating solid tumours: A review with structure-activity relationship insights.
Puri S, Juvale K.
Eur J Med Chem (2020) 199 : 112393 -112393
PubMed 32388280 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5221129 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5221129 Ki = 2.0 nM 8.70