Assay Detail

CHEMBL5234565

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Functional

Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay

ChEMBL ↗

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Target

MCF7 (CHEMBL387) ↗

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Primary target MCF7

CHEMBL387

Anchored from Assay target.

Protein identity MCF7

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	MCF7
Confidence	1 — Organism
Curated By	Autocuration

Target

MCF7 (CHEMBL387) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Resveratrol - A comprehensive review of recent advances in anticancer drug design and development.

Ahmadi R, Ebrahimzadeh MA.
Eur J Med Chem (2020) 200 : 112356 -112356
PubMed 32485531 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	4.32	4.58

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL248499	—	—	1	4.58
CHEMBL165	RESVERATROL	3.0	1	4.05

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL248499	—	IC50	=	26300.0	nM	4.58
CHEMBL165	RESVERATROL	IC50	=	88200.0	nM	4.05