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Assay Detail

CHEMBL5234569

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Resveratrol - A comprehensive review of recent advances in anticancer drug design and development.
Ahmadi R, Ebrahimzadeh MA.
Eur J Med Chem (2020) 200 : 112356 -112356
PubMed 32485531 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.64 4.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296411 TRISMETHOXYRESVERATROL 1 4.85
CHEMBL3765737 2 4.72
CHEMBL165 RESVERATROL 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296411 TRISMETHOXYRESVERATROL IC50 = 14000.0 nM 4.85
CHEMBL3765737 IC50 = 18900.0 nM 4.72
CHEMBL3765737 IC50 = 44300.0 nM 4.35
CHEMBL165 RESVERATROL IC50 = 130000.0 nM -