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Assay Detail

CHEMBL5234597

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibtion of CYP1A (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Cytochrome P450 1A (CHEMBL3544905)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Resveratrol - A comprehensive review of recent advances in anticancer drug design and development.
Ahmadi R, Ebrahimzadeh MA.
Eur J Med Chem (2020) 200 : 112356 -112356
PubMed 32485531 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.34 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296411 TRISMETHOXYRESVERATROL 1 8.52
CHEMBL5287750 1 6.85
CHEMBL165 RESVERATROL 3.0 1 6.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296411 TRISMETHOXYRESVERATROL IC50 = 3.0 nM 8.52
CHEMBL5287750 IC50 = 140.0 nM 6.85
CHEMBL165 RESVERATROL IC50 = 230.0 nM 6.64