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Assay Detail

CHEMBL5234847

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human NCI-H522 cells assessed as inhibition of cell growth incubated for 3 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H522
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H522 (CHEMBL614387)
Type CELL-LINE
Organism Homo sapiens

Publication

Epoxide containing molecules: A good or a bad drug design approach.
Gomes AR, Varela CL, Tavares-da-Silva EJ, Roleira FMF.
Eur J Med Chem (2020) 201 : 112327 -112327
PubMed 32526552 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL101871 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL101871 IC50 = 70.0 nM 7.16