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Assay Detail

CHEMBL5234867

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type MCF-7aro
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Aromatase (CHEMBL1978)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Epoxide containing molecules: A good or a bad drug design approach.
Gomes AR, Varela CL, Tavares-da-Silva EJ, Roleira FMF.
Eur J Med Chem (2020) 201 : 112327 -112327
PubMed 32526552 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.07 5.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2058266 1 5.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2058266 IC50 = 8500.0 nM 5.07