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Assay Detail

CHEMBL5234896

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human SK-MES-1 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-MES-1
Confidence 1 — Organism
Curated By Autocuration

Target

SK-MES-1 (CHEMBL614923)
Type CELL-LINE
Organism Homo sapiens

Publication

Epoxide containing molecules: A good or a bad drug design approach.
Gomes AR, Varela CL, Tavares-da-Silva EJ, Roleira FMF.
Eur J Med Chem (2020) 201 : 112327 -112327
PubMed 32526552 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.64 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL250785 CINOBUFAGIN 1 5.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL250785 CINOBUFAGIN IC50 = 2300.0 nM 5.64