Assay Detail
Functional
CHEMBL5235035
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Antiviral activity against HCV infected in human Huh-7.5.1 cells assessed as reduction in viral infection incubated for 48 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7.5.1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.40 | 10.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL466993 | — | — | 1 | 10.40 |
| CHEMBL438139 | ROCAGLAMIDE | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL466993 | — | EC50 | = | 0.04 | nM | 10.40 |
| CHEMBL438139 | ROCAGLAMIDE | EC50 | = | 4.0 | nM | 8.40 |