Assay Detail
Binding
CHEMBL5235155
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Inhibition of IDO1 in human HeLa cells assessed as inhibition of kynurenine production incubated for 30 mins by microplate reader based analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Diverse chemical space of indoleamine-2,3-dioxygenase 1 (Ido1) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.51 | 8.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5203175 | — | — | 1 | 8.02 |
| CHEMBL5287332 | — | — | 1 | 7.00 |
| CHEMBL5278502 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5203175 | — | IC50 | = | 9.6 | nM | 8.02 |
| CHEMBL5287332 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5278502 | — | IC50 | < | 1000.0 | nM | - |