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Assay Detail

CHEMBL5235503

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at rat FPR1 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Cell Type CHO
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.
Maciuszek M, Cacace A, Brennan E, Godson C, Chapman TM.
Eur J Med Chem (2021) 213 : 113167 -113167
PubMed 33486199 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.82 8.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4784510 BMS-986235 1.0 1 8.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4784510 BMS-986235 EC50 = 1.5 nM 8.82