Assay Detail
Binding
CHEMBL5235595
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-LSD from human 5-HT2C expressed in human HEK cells assessed as inhibition constant by FLIPR assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
β-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.60 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL338115 | — | — | 1 | 6.04 |
| CHEMBL295234 | — | — | 1 | 5.72 |
| CHEMBL340807 | HARMALINE | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL338115 | — | Ki | = | 920.0 | nM | 6.04 |
| CHEMBL295234 | — | Ki | = | 1900.0 | nM | 5.72 |
| CHEMBL340807 | HARMALINE | Ki | = | 9400.0 | nM | 5.03 |