Assay Detail
Functional
CHEMBL5235977
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiinflammatory activity in macrophages assessed as reduction in LPS-induced NO production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Not specified |
| Cell Type | Macrophage |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
An overview of hydroxypyranone and hydroxypyridinone as privileged scaffolds for novel drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.62 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2397748 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2397748 | — | IC50 | = | 23950.0 | nM | 4.62 |