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Assay Detail

CHEMBL5235979

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HCV
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Hepacivirus hominis
Confidence 1 — Organism
Curated By Autocuration

Target

Hepatitis C virus (CHEMBL379)
Type ORGANISM
Organism Hepacivirus hominis

Publication

An overview of hydroxypyranone and hydroxypyridinone as privileged scaffolds for novel drug discovery.
He M, Fan M, Peng Z, Wang G.
Eur J Med Chem (2021) 221 : 113546 -113546
PubMed 34023737 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.58 5.59

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2031845 1 5.59
CHEMBL5287176 1 5.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2031845 EC50 = 2550.0 nM 5.59
CHEMBL5287176 EC50 = 2740.0 nM 5.56