Assay Detail
Binding
CHEMBL5236197
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Inhibition of sEH (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.35 | 8.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4066332 | — | — | 1 | 8.39 |
| CHEMBL5281274 | — | — | 1 | 5.77 |
| CHEMBL603 | ZAFIRLUKAST | 4.0 | 1 | 5.70 |
| CHEMBL5273108 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4066332 | — | IC50 | = | 4.1 | nM | 8.39 |
| CHEMBL5281274 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL603 | ZAFIRLUKAST | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL5273108 | — | IC50 | = | 2900.0 | nM | 5.54 |