Assay Detail
Binding
CHEMBL5236771
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Binding affinity to human wild type HIF2alpha assessed as dissociation constant by calorimetry assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Furazans in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 8.75 | 9.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2311932 | — | — | 1 | 9.77 |
| CHEMBL5276412 | — | — | 1 | 9.66 |
| CHEMBL2311967 | — | — | 1 | 9.59 |
| CHEMBL3597786 | — | — | 1 | 7.64 |
| CHEMBL2311933 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2311932 | — | Kd | = | 0.17 | nM | 9.77 |
| CHEMBL5276412 | — | Kd | = | 0.22 | nM | 9.66 |
| CHEMBL2311967 | — | Kd | = | 0.26 | nM | 9.59 |
| CHEMBL3597786 | — | Kd | = | 23.0 | nM | 7.64 |
| CHEMBL2311933 | — | Kd | = | 80.0 | nM | 7.10 |