Assay Detail
Functional
CHEMBL5236776
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Antiproliferative activity against human HeLa cells assessed as reduction in cell viability
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Furazans in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.28 | 8.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3545369 | EPACADOSTAT | 3.0 | 1 | 8.13 |
| CHEMBL584991 | — | — | 1 | 7.72 |
| CHEMBL585186 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3545369 | EPACADOSTAT | EC50 | = | 7.4 | nM | 8.13 |
| CHEMBL584991 | — | EC50 | = | 19.0 | nM | 7.72 |
| CHEMBL585186 | — | EC50 | = | 1000.0 | nM | 6.00 |