Assay Detail
Functional
CHEMBL5236852
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Antimalarial activity against drug sensitive Plasmodium falciparum 3D7
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Furazans in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.30 | 4.65 |
| EC90 | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1235045 | — | — | 2 | 4.65 |
| CHEMBL1232960 | — | — | 2 | 4.13 |
| CHEMBL1232973 | — | — | 2 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1235045 | — | EC50 | = | 22500.0 | nM | 4.65 |
| CHEMBL1232960 | — | EC50 | = | 74400.0 | nM | 4.13 |
| CHEMBL1232973 | — | EC50 | = | 75300.0 | nM | 4.12 |
| CHEMBL1235045 | — | EC90 | = | 75.9 | uM | - |
| CHEMBL1232960 | — | EC90 | > | 200.0 | uM | - |
| CHEMBL1232973 | — | EC90 | > | 170.0 | uM | - |