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Assay Detail

CHEMBL5236853

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against drug resistant Plasmodium falciparum KI
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Furazans in Medicinal Chemistry.
Mancini RS, Barden CJ, Weaver DF, Reed MA.
J Med Chem (2021) 64 : 1786 -1815
PubMed 33569941 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 4.73 4.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1235045 1 4.73
CHEMBL1232973 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1235045 EC50 = 18600.0 nM 4.73
CHEMBL1232973 EC50 = 144000.0 nM -