Assay Detail
Binding
CHEMBL5236922
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Partial agonist activity at D2 receptor (unknown origin) assessed as beta arrestin-2 recruitment
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Potent and Subtype-Selective Dopamine D<sub>2</sub> Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.20 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4445841 | — | — | 1 | 8.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4445841 | — | EC50 | = | 6.3 | nM | 8.20 |