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Assay Detail

CHEMBL5236987

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HepG2 cells by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Marine Natural Products: A Potential Source of Anti-hepatocellular Carcinoma Drugs.
Ren X, Xie X, Chen B, Liu L, Jiang C, Qian Q.
J Med Chem (2021) 64 : 7879 -7899
PubMed 34128674 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.80 6.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5285742 1 6.23
CHEMBL5271455 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5285742 IC50 = 590.0 nM 6.23
CHEMBL5271455 IC50 = 4300.0 nM 5.37