Assay Detail

CHEMBL5237293

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Functional

Antiviral activity against Chikungunya virus

ChEMBL ↗

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Target

Chikungunya virus (CHEMBL4296563) ↗

Open DB target context

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Chikungunya virus (CHEMBL4296563) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Chikungunya virus

CHEMBL4296563

Anchored from Assay target.

Protein identity Chikungunya virus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Chikungunya virus
Confidence	1 — Organism
Curated By	Autocuration

Target

Chikungunya virus (CHEMBL4296563) ↗

Type	ORGANISM
Organism	Chikungunya virus

Publication

Andrographolide and its derivatives: Current achievements and future perspectives.

Zhang H, Li S, Si Y, Xu H.
Eur J Med Chem (2021) 224 : 113710 -113710
PubMed 34315039 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.22	6.22

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL186141	ANDROGRAPHOLIDE	3.0	1	6.22

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL186141	ANDROGRAPHOLIDE	IC50	=	600.0	nM	6.22