Assay Detail
Binding
CHEMBL5237383
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human DYRK1A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (CHEMBL2292) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of Cdc2-like Kinase 2 Inhibitors: Achievements and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.39 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4297639 | LORECIVIVINT | 3.0 | 1 | 7.57 |
| CHEMBL3589660 | — | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4297639 | LORECIVIVINT | IC50 | = | 26.9 | nM | 7.57 |
| CHEMBL3589660 | — | IC50 | = | 61.0 | nM | 7.21 |