Assay Detail
Binding
CHEMBL5237438
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Inhibition of KDM5A (unknown origin ) by Alphalisa analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pharmacological inhibition of KDM5A for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.55 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5272926 | — | — | 1 | 8.36 |
| CHEMBL4637168 | — | — | 1 | 7.82 |
| CHEMBL5277129 | — | — | 1 | 7.52 |
| CHEMBL5276550 | — | — | 1 | 6.50 |
| CHEMBL5281316 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5272926 | — | IC50 | = | 4.37 | nM | 8.36 |
| CHEMBL4637168 | — | IC50 | = | 15.1 | nM | 7.82 |
| CHEMBL5277129 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL5276550 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL5281316 | — | IC50 | > | 60000.0 | nM | - |