Assay Detail
Functional
CHEMBL5237461
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Antiproliferative activity against human Caco-2 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Caco-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pharmacological inhibition of KDM5A for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.06 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5285505 | — | — | 1 | 6.52 |
| CHEMBL5277258 | — | — | 1 | 5.60 |
| CHEMBL5277129 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5285505 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL5277258 | — | EC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL5277129 | — | EC50 | > | 30000.0 | nM | - |