Assay Detail
Binding
CHEMBL5237465
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Inhibition of KDM5A (unknown origin ) by TR-FRET assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pharmacological inhibition of KDM5A for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.96 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1982368 | — | — | 1 | 6.64 |
| CHEMBL5272568 | — | — | 1 | 6.08 |
| CHEMBL3188597 | — | — | 1 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1982368 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL5272568 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL3188597 | — | IC50 | = | 6800.0 | nM | 5.17 |