Assay Detail
Binding
CHEMBL5237496
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Tau (unknown origin) phosphorylation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Microtubule-associated protein tau (CHEMBL1293224) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Imidazo[1,2-b]pyridazine as privileged scaffold in medicinal chemistry: An extensive review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.11 | 8.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270781 | — | — | 1 | 8.04 |
| CHEMBL5269379 | — | — | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270781 | — | IC50 | = | 9.2 | nM | 8.04 |
| CHEMBL5269379 | — | IC50 | = | 660.0 | nM | 6.18 |