Assay Detail
Functional
CHEMBL5237624
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Antibacterial activity against Bacillus subtilis NBRC/ATCC 111470 assessed as reduction in bacterial growth incubated for 18 hrs by resazurin dye based microplate reader analysis
10
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus subtilis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Oxygenated Cyclohexene Derivatives from the Stem and Root Barks of <i>Uvaria pandensis</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 4.97 | 5.06 |
| MIC | 5 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL523296 | UVARETIN | — | 2 | 5.06 |
| CHEMBL5274935 | — | — | 2 | 5.06 |
| CHEMBL5278583 | — | — | 2 | 5.01 |
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | 4.75 |
| CHEMBL5272880 | — | — | 2 | - |
| CHEMBL5268712 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL523296 | UVARETIN | EC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL5274935 | — | EC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL5278583 | — | EC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL174 | AMPICILLIN | EC50 | = | 17900.0 | nM | 4.75 |
| CHEMBL5272880 | — | EC50 | = | 1154100.0 | nM | - |
| CHEMBL5268712 | — | MIC | > | 725000.0 | nM | - |
| CHEMBL5278583 | — | MIC | > | 725000.0 | nM | - |
| CHEMBL5272880 | — | MIC | > | 725000.0 | nM | - |
| CHEMBL523296 | UVARETIN | MIC | > | 725000.0 | nM | - |
| CHEMBL5274935 | — | MIC | > | 725000.0 | nM | - |