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Assay Detail

CHEMBL5237678

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PRC2 (unknown origin) using H3K27me0 as peptide substrate by LC-MS based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

An overview of the development of EED inhibitors to disable the PRC2 function.
Liu KL, Zhu K, Zhang H.
RSC Med Chem (2022) 13 : 39 -53
PubMed 35224495 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.63 7.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4065484 1 7.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4065484 IC50 = 23.4 nM 7.63