Assay Detail

CHEMBL5237779

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Functional

Antiproliferative activity against multidrug resistant human CEM/VLB100 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	CEM/VLB100
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Bioactive Aurones, Indanones, and Other Hemiindigoid Scaffolds: Medicinal Chemistry and Photopharmacology Perspectives.

Lazinski LM, Royal G, Robin M, Maresca M, Haudecoeur R.
J Med Chem (2022) 65 : 12594 -12625
PubMed 36126323 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL144647	—	—	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL144647	—	IC50	=	2.0	nM	8.70