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Assay Detail

CHEMBL5237804

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 30 mins by spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Agaricus bisporus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosinase (CHEMBL3318)
Type SINGLE PROTEIN
Organism Agaricus bisporus

Publication

Bioactive Aurones, Indanones, and Other Hemiindigoid Scaffolds: Medicinal Chemistry and Photopharmacology Perspectives.
Lazinski LM, Royal G, Robin M, Maresca M, Haudecoeur R.
J Med Chem (2022) 65 : 12594 -12625
PubMed 36126323 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.47 7.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5274383 1 7.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5274383 IC50 = 34.0 nM 7.47