Assay Detail
Binding
CHEMBL5237973
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MMP12 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting Aggrecanases for Osteoarthritis Therapy: From Zinc Chelation to Exosite Inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.47 | 5.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL307145 | PYROGALLOL | -1.0 | 1 | 5.69 |
| CHEMBL69863 | PICEATANNOL | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL307145 | PYROGALLOL | Ki | = | 2030.0 | nM | 5.69 |
| CHEMBL69863 | PICEATANNOL | Ki | = | 5570.0 | nM | 5.25 |