Assay Detail
Functional
CHEMBL5238569
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Inhibition of LPS-induced TNF-alpha secretion in mouse primary peritoneal macrophages by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Peritoneal macrophage |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery and Optimization of <i>N</i>-Acyl-6-sulfonamide-tetrahydroquinoline Derivatives as Novel Non-Steroidal Selective Glucocorticoid Receptor Modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.06 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5280308 | — | — | 1 | 5.11 |
| CHEMBL2013139 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5280308 | — | IC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL2013139 | — | IC50 | = | 10000.0 | nM | 5.00 |