Assay Detail
Functional
CHEMBL5239867
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Cytotoxicity against human LN-18 cells assessed as cell viability measured upto 108 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LN-18 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New class of fused [3,2-b][1,2,4]triazolothiazoles for targeting glioma in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.88 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5286057 | — | — | 1 | 5.05 |
| CHEMBL5270077 | — | — | 1 | 4.90 |
| CHEMBL5270610 | — | — | 1 | 4.90 |
| CHEMBL5281021 | — | — | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5286057 | — | IC50 | = | 8970.0 | nM | 5.05 |
| CHEMBL5270077 | — | IC50 | = | 12560.0 | nM | 4.90 |
| CHEMBL5270610 | — | IC50 | = | 12680.0 | nM | 4.90 |
| CHEMBL5281021 | — | IC50 | = | 21510.0 | nM | 4.67 |