Assay Detail
Binding
CHEMBL5240307
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Agonist activity at FFAR1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.40 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2385460 | — | — | 1 | 8.89 |
| CHEMBL1829174 | FASIGLIFAM | 3.0 | 1 | 8.11 |
| CHEMBL5219102 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2385460 | — | EC50 | = | 1.3 | nM | 8.89 |
| CHEMBL1829174 | FASIGLIFAM | EC50 | = | 7.7 | nM | 8.11 |
| CHEMBL5219102 | — | EC50 | = | 6500.0 | nM | 5.19 |