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Assay Detail

CHEMBL5241270

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Functional
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 0 to 5 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach.
Tanwar AK, Dhiman N, Kumar A, Jaitak V.
Eur J Med Chem (2021) 213 : 113037 -113037
PubMed 33257172 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL30707 COUMESTROL 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL30707 COUMESTROL IC50 = 50000.0 nM 4.30