Assay Detail
Functional
CHEMBL5241271
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Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 2 days by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.83 | 4.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL253896 | XANTHOHUMOL | 2.0 | 1 | 4.88 |
| CHEMBL492828 | ISOXANTHOHUMOL | — | 1 | 4.82 |
| CHEMBL479351 | XANTHOHUMOL C | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL253896 | XANTHOHUMOL | IC50 | = | 13300.0 | nM | 4.88 |
| CHEMBL492828 | ISOXANTHOHUMOL | IC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL479351 | XANTHOHUMOL C | IC50 | = | 15700.0 | nM | 4.80 |