Assay Detail
Binding
CHEMBL5241281
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.54 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150 | KAEMPFEROL | 1.0 | 1 | 6.54 |
| CHEMBL8145 | DAIDZEIN | 2.0 | 1 | 6.54 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 6.54 |
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150 | KAEMPFEROL | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL8145 | DAIDZEIN | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL50 | QUERCETIN | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL44 | GENISTEIN | IC50 | = | 290.0 | nM | 6.54 |