Assay Detail
Functional
CHEMBL5241503
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Antiplasmodial activity against Plasmodium falciparum DD2 assessed as growth inhibition
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An insight in anti-malarial potential of indole scaffold: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.02 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5286831 | — | — | 1 | 7.51 |
| CHEMBL5280687 | — | — | 1 | 7.08 |
| CHEMBL1098875 | — | — | 1 | 7.00 |
| CHEMBL5269356 | — | — | 1 | 6.91 |
| CHEMBL5278994 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5286831 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL5280687 | — | IC50 | = | 84.1 | nM | 7.08 |
| CHEMBL1098875 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5269356 | — | IC50 | = | 123.0 | nM | 6.91 |
| CHEMBL5278994 | — | IC50 | = | 238.0 | nM | 6.62 |